Palliative care services are often a major component of the care of infants, children and adolescents who have complex medical, physical, developmental, and psychosocial needs. At the Elizabeth Seton Pediatric Center we have placed special emphasis on the needs of residents, families and staff in anticipation of and during times of irreversible illness and death. The goal is to provide comfort from the disease process, while also addressing psychological, social and spiritual matters not only for the resident, but also for the family and care givers. Quality of life is improved through traditional and complementary treatments, including pain management, Reiki, mental health services and interfaith, interdenominational pastoral care. Staff education in palliative care methods and practices is ongoing.